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To find out how thigh circumference affects health, Harvard Health reported that Danish scientists evaluated 2,816 men and women ages 35 to 65 who were free of heart disease, stroke, and cancer when they joined the study in the late ’80s. Each participant provided a detailed health history and each underwent comprehensive examinations that included measurements of height, weight, and thigh, hip, and waist circumferences, as well as body fat percentage, which was determined by the highly accurate impedance method.
Researchers tracked the volunteers for an average of 12.5 years. They found people with big thighs had a lower risk of heart disease and premature death than those with thin thighs. A thigh circumference (measured where the thigh meets the butt) of about 62 cm (about 24.4 inches) was most protective; bigger thighs provided little if any extra benefit, but progressively thinner thighs were linked to progressively higher risks. The predictive value of thigh size held up even after the scientists accounted for other indicators of body composition, including waist circumference, BMI, height, and body fat percentage. And thigh size remained a strong independent predictor even after researchers adjusted for risk factors such as smoking, exercise, alcohol use.
It’s a fact that, fat cells in the lower part of the body seem to vacuum up harmful fatty acids that are released into the blood when fat-laden foods are digested. Fat cells in the upper body also store up free fatty acids, but are quick to pour them back into the blood in response to stress-induced surges of adrenaline. And abdominal fat cells (around your midsection) produce larger amounts of cytokines, chemicals that trigger harmful inflammation, while lower-body fat cells produce productive chemicals, including leptin and adiponectin.
