I use Eudora to filter email IN instead of OUT. I have a ton of words on my list, but I bet it's still a lost smaller than most people's spam word list. :P
There are obviously a few that get through and a small handful I accidentally delete, but with 2000+ going into the "in box" and everything else where it should be, it's worth it to hit "delete" on everything in the in box once a day.