3300 miles
I've done it 8 times
3 days hard driving

Do at least like 900 miles the first day...sleep in hotel.
Do the same the next day.
On the third day you hit Georgia abgout 9pm....you turn to the wife and say "Might as well truck on through to Orlando" (its about 500 miles)
Pull into the Hyatt Regency Grand Cyprus 3am
Peice of cake ;-)))